Biosolve Solvents for Chromatography
Chromatography
Solvents & Formulations
Biosolve has developed different lines of HPLC solvents and mass spectrometry solvents. Standard HPLC, UHPLC, SFC… depending on the liquid chromatography technique you use, select the solvent line fitting your needs.
ULC/MS - CC/SFC Solvents
Biosolve ULC/MS – CC/SFC solvents checked and guaranteed to meet the highest demand for any detection mode connected to ultra-high-performance liquid chromatography (UHPLC), convergence chromatography (CC) and supercritical fluid chromatography (SFC). Extensive QC testing with mass-spectrometer, UV & PDA detectors and ICP-MS ensures the highest specifications for chemical purity, high UV transmission, lowest peak impurities by gradient elution tests and low ionic background.
All ULC/MS-CC/SFC solvents are filtered at 0.1μm and packed under inert gas for better shelf life. Standard packages are available in 1L, 2.5L, PTFE lined amber bottles and for some solvents stainless steel containers are available that can be equipped with dip pipe delivery devices from 25L to 1500L volume.
LC-MS Solvents
LC-MS grade solvents for routine quality chromatography work. Biosolves LC-MS solvents have low cations level and good HPLC, UHPLC and MS performance. All are filtered through 0.2 µm filters.
HPLC SUPRA-GRADIENT Solvents
Biosolves HPLC Supra-Gradient solvents guaranteed specifications are often unique on the market including ultra-low fluorescent impurity levels, outstanding high UV transmission, minimum peak impurities, and very low drift in gradient HPLC.
HPLC Solvents
Biosolve proposes a complete range of HPLC solvents available in different grades: regular HPLC, standard HPLC, preparative HPLC. Please, select the quality fitting your needs.
Solvents for Gas Chromatography
For gas chromatography, Biosolve offers GC-solvents with high purity, high transmittance and low level of fluorescent impurities. Available for GC-Headspace and for LV-GC, please select the line corresponding to your application.
GC Headspace solvents
Biosolve offers solvents specifically developed for the analysis of Organic Volatile Impurities - OVI - by GC-Headspace technique.
Analysis of OVI using GC-Headspace techniques has become a major control procedure in pharmaceutical and food related industries. It requires solvents with a high purity and virtually no background in the volatile impurities range.
Biosolve’s GC Headspace solvents are optimized for accurate analysis of OVI. Every single production batch is specifically evaluated by analysis against OVI standard to ensure the absence of interfering peaks in the GC chromatogram, by both polar and non-polar GC columns. They are suitable for the analysis of OVI as described by the ICH, USP & EP methods.
LV-GC SuperTrace Solvents
Large Volume GC Solvents - LV/GC SuperTrace®
This solvents range is suitable for ultimate organic trace analysis; checked for ppb levels of Poly-Aromatic Hydrocarbons (PAH’s), Furans, PCB’s, Pesticides, Mineral oil hydrocarbons (MOSH-MOAH) in the range of C10 to C40, and for other residual organic contaminants. Each batch is fully analyzed after 1000:1 concentration with HPLC-PDA, GC-FID, GC-ECD and GC-MS.
All solvents are filtered through 0.2μm and packed under inert gas for better shelf-life.
Reference Standards Solvents for Gas Chromatography
The FDA, USP and EP all recognize the use of secondary standards and working standards that are established with reference to the corresponding primary standard.
Biosolve offers pharmaceutical laboratories and manufacturers a broad range of secondary GC reference standards for various chromatographic and analytical applications. Our secondary GC standards give a convenient and cost-effective alternative to the pharmacopeias primary standards and allow laboratories to focus resources on their core activities rather than preparing internal working standards.
Biosolve secondary GC reference standards are traceable to the current lots of the United States Pharmacopeia (USP); or to European Pharmacopoeia (EP) and British Pharmacopoeia (BP) if available.
Most of our GC reference standards are completely synthetic and typically over 99.9% pure by GC-FID. Identifications determined by GC-MS, FTIR and 1H NMR and reported in the certificate of analysis of each manufactured lot.
Spectrograde
Biosolve offers Spectrograde solvents - Spectrophotometric solvents - with guaranteed ultra-low fluorescence and/or low UV absorbance levels. Theses solvents are also suitable for IR analysis. Depending on your application, please select the quality fitting your needs.
The Spectrofluopure solvents are Biosolve’s highest quality of Spectrophotometric solvents. Specifically developed for UV detection, they are rigorously tested for their ultra-clean UV spectrum.
Spectropure Biosolve’s solvents are high-purity and low residue Spectrophotometric solvents. With low fluorescence and/or low UV absorbance levels, they meet the requirements of UV analysis as well as IR analysis.
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About The Author
Susan Massie, Sales & Marketing Director, Greyhound Chromatography and Allied Chemicals Email: sue@greyhoundchrom.com
Susan Massie is the Sales & Marketing Director for Greyhound Chromatography and Allied Chemicals, affectionately known as 'Greyhound' in our scientific community. Greyhound was founded by Susan's husband Paul Massie more than 40 years ago, Susan hasn't been in the business for all of that time but has been involved with Greyhound for over 19 years. Greyhound continues to grow, expanding into new markets and taking on the challenges of our ever changing environment. It's heartwarming to witness the world waking up to the fact that we are damaging our planet on a daily basis. Every action we take has a direct effect on our planet and the world we leave behind for future generations. Susan is passionate about climate change and is happy to work in an industry that can have a direct effect on reducing the impact of our actions on the environment. All of the team at Greyhound take our responsibilities very seriously, the products that we supply are used by the world's leading scientists and chemists as they endeavour to monitor and repair the environment. All is not lost, if we all take responsibility for our actions, from reducing our waste and reusing or recycling our material collateral we can make a difference. The internet is full of useful advice and guidance, Susan is proud to contribute to that wealth of knowledge whenever she can.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. Greyhound provides technical advice and distribution of Certified Reference Standards and Materials, Laboratory Consumables, Solvents and Reagents across all scientific disciplines. Greyhound Chromatography offers over 1 Million products from its UK warehouse. The team at Greyhound are proud to support the work of the world's leading scientists and chemists as they challenge the abuse of our planet and try to make a difference to the world we leave behind for our ancestors.
You can view Susan's Linked In Profile here https://www.linkedin.com/in/susan-massie-79ab4121/
You can view Greyhound Chromatography’s LinkedIn page here https://www.linkedin.com/company/greyhound-chromatography/