Hamilton PRP-X500 is a superficially porous polymeric anion exchange column.

The methacrylate polymeric coating of the PRP-X500 provides a more hydrophilic surface, preventing hydrophobic interaction sample losses typically seen on other commercially available protein HPLC columns.

Recovery of sample is excellent with PRP-X500 and the support’s limited permeability prevents proteins from entering the pores and unfolding, which causes peak ghosting. The superficially porous properties of the packing material improves mass-transfer, shortening the diffusion path of the analyte. This results in shortened run times, improved resolution, and sharp sample bands.

  • Pore Size: Superficially porous
  • Exchange Capacity: 1.6 meq/gm
  • Material: Methacrylamido propyl trimethyl ammonium chloride (SAX)
  • Applications: Proteins, peptides, and DNA/RNA