Coned fittings offer enhanced pressure holding abilities for demanding fluidic applications. Most Upchurch Coned Fittings have been engineered to work in the high pressure zone of chromatography systems – the region between the outlet of the pump and the inlet of the column – where the physical stresses on the fittings are generally high, with inline pressures reaching 6,000 psi or higher and in UHPLC applications pressures can reach up to 20000psi or higher.